Skip directly to content


ENBREL is a prescription medicine that can be self-injected. It is used to treat six long-term inflammatory diseases: moderate to severe rheumatoid arthritis (RA), moderate to severe plaque psoriasis, chronic severe plaque psoriasis in children and adolescents, psoriatic arthritis, moderate to severe juvenile idiopathic arthritis (JIA), and ankylosing spondylitis (AS).

ENBREL is grouped within a class of medications called biologic response modifiers, or biologics. By working on the immune system, biologics block proteins that contribute to the disease process. Because ENBREL suppresses the immune system, patients are at a greater risk of getting serious infections.


The science behind ENBREL

Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with certain inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis may have too much TNF in their bodies. ENBREL reduces levels of the active form of TNF.


The clinical history of ENBREL

  • ENBREL was the first biologic approved for moderate to severe rheumatoid arthritis
  • ENBREL has a known side effect profile
  • ENBREL has over 10 years of continuous safety data in patients with rheumatoid arthritis


How ENBREL is taken

Taking ENBREL can be simple and convenient. ENBREL is injected (by you or a trained caregiver) just under the skin in the comfort of your own home. ENBREL is available in multiple injection options, and with the design of the ENBREL® Auto-injector, you'll never even have to see the needle. Schedule a training session with your healthcare professional to learn the proper way to self-inject.

Click here to learn more about injecting ENBREL and to view step-by-step injection videos.

If you ever have questions about injecting ENBREL please speak to your healthcare professional, or call 0800 ENBREL (0800 362 735).